WebAug 27, 2024 · Finally, we demonstrated that MALAT1 acts as a competing endogenous RNA by directly binding to miR-124 to regulate AGA-induced MCP-1 expression in … WebJul 1, 2024 · We hypothesized that MALAT1 was involved in the LPS-induced activation of microglial cells and proinflammatory cytokine production. MALAT1 was inhibited in the LPS-activated microglia cells BV2 and N9 in vitro by mean of transfection of siRNA-MALAT1 ( …
Table 1 MALAT1 Mediates α-Synuclein Expression through miR …
WebMALAT1, originally identified in pulmonary adenocarcinoma, is among the most abundant lncRNA in the nervous system. It is described as heavily expressed in different types of … All experiments with human materials were approved by the local administration and were performed in accordance with the respective national, federal and institutional regulations. Human microglia were isolated from histologically healthy brain tissue removed during brain surgery for the treatment of epilepsy in five … See more CD-1 mice were used. All animal experiments were approved by local administration and were performed in accordance to the … See more Microglia were FACS-sorted from up to six different regions of the CNS of healthy and diseased brains (see gating strategy shown in … See more For juvenile and adult mice, after transcardial perfusion with PBS, brains were fixed for 4 h in 4% PFA, dehydrated in 30% sucrose and embedded in Tissue-Tek O.C.T. compound (Sakura Finetek Germany GmbH). … See more After transcardial perfusion with PBS, brains were roughly minced and homogenized with a potter in HBSS containing 15 mM HEPES buffer and 0.54% glucose. … See more riftbreaker cracked
Long noncoding RNA MALAT1 acts as a competing endogenous …
WebJul 1, 2024 · MALAT1 was a cancer-associated lncRNAs positively relating to tumorigenesis, migration, invasion, and growth of human cancers. Overexpressed MALAT1 significantly … WebAug 20, 2024 · Malat1 was initially found to be upregulated in various tumor tissues and was thought to participate in the development and metastasis of cancer [ 14 ]. Subsequently, a clinical study... WebJul 1, 2024 · Long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) was widely recognized to be implicated in human cancer, vascular … riftbreaker coop mod