Web1 feb. 2012 · Vibrio cholerae excreted by cholera patients is "hyperinfectious" (HI), which can be modeled by passage through infant mice. Immunization of adult female mice with … Web6 dec. 2005 · Incorporation of this hyperinfectious state into our disease model provides a much better fit with the observed epidemic pattern of cholera. These findings help to substantiate the clinical relevance of laboratory observations regarding the hyperinfectious state, and underscore the critical importance of human-to-human versus environment-to …

Intraspecies variation in the emergence of hyperinfectious

WebHartley et al. in 2006 extended Codeco’s model by adding a hyperinfectious state of the pathogen, representing the ”explosive” infectivity of freshly shed Vibro Cholerae, based on the laboratory observations [7]. Web6 dec. 2005 · They assumed that the number of hyperinfectious bacteria (i.e., those from fresh feces of a sick patient) necessary to cause disease was smaller than the … shona and david

Emergence of a

Web12 feb. 2014 · The hyperinfectious state only makes the necessary infectious dose (or the IC 50) much lower. Given that the “human-to-human” transmission is only a mathematical proxy of the impact of the hyperinfectious bacteria, clean water provision should have an impact on human-to-human transmission, even if it may not stop transmission completely. WebHyperinfectious (class B H ) and less-infectious bacteria concentrations (class B L ) are measured with respect to their infectious doses. Bacteria transitions to the less infectious … Webinfectivity, which is called hyperinfectious. But the hyperinfectious bacteria decays in a matter of hours into a lower infectious state. It means that hyperinfectious bacteria can only be ingested if there are meeting (i.e. using the same river or toilet on the same day) between susceptible with infected individuals. shona armstrong