WebPotentially fatal lung toxicity occurs in 12-20% of leukemic patients treated with cytarabine especially at intermediate to high doses, usually presenting as noncardiogenic pulmonary edema (NCPE). Anecdotally the association between cytarabine and the onset of bronchiolitis obliterans organizing pneumonia (BOOP) has been reported. WebApr 9, 2024 · Most drug-induced pulmonary toxicities involve the parenchyma, thus, interstitial infiltrates may be demonstrated on radiographs. Pleural fluid may be the only finding. However, the …
Chemotherapy-Related Drug-Induced Lung Injury
WebJul 13, 2007 · Amiodarone pulmonary toxicity (APT) is a common lung injury, with a prevalence of between 1% and 15% of the treated population. 36 An estimated incidence … WebSep 1, 2000 · Pulmonary drug toxicity is increasingly being diagnosed as a cause of acute and chronic lung disease. Numerous agents including cytotoxic and noncytotoxic drugs have the potential to cause … simply piano app for fire
Cytarabine-related lung infiltrates on high resolution ... - PubMed
WebNov 11, 2024 · The patients with clinical suspicion of chemotherapy-induced lung toxicity underwent further evaluation with chest radiograph, HRCT or CECT chest, spirometry, DLCO, FOB, BAL fluid examination, and TBLB. ... As is true with most cases of drug-induced lung disease, the diagnosis of chemotherapy-induced lung disease can be … WebJul 21, 2024 · Drug-induced lung injury resulting in a combination of nonspecific interstitial pneumonia and hypersensitivity pneumonitis patterns caused by lenalidomide and bortezomib therapy in a patient with relapsed multiple myeloma. ... Diffuse alveolar damage is one of the most common histologic manifestations of pulmonary drug toxicity and … WebMay 24, 2024 · PHARMACOLOGY AND PATHOGENESIS OF LUNG INJURY The antineoplastic effect of bleomycin is unique among anticancer agents, and is thought to involve the production of single- and double-strand breaks in DNA (scission) by a complex of bleomycin, ferrous ions, and molecular oxygen [2,6,7]. simply piano app for android